Translational Medicine in CNS Drug Development
  • Release Date : 18 June 2019
  • Publisher : Academic Press
  • Categories : Medical
  • Pages : 458 pages
  • ISBN 13 : 9780128031643
  • ISBN 10 : 0128031646
Score: 4
From 245 Ratings

Synopsis : Translational Medicine in CNS Drug Development written by George G. Nomikos, published by Academic Press which was released on 18 June 2019. Download Translational Medicine in CNS Drug Development Books now! Available in PDF, EPUB, Mobi Format. Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the development and approval of drugs for their treatment have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and CNS to pharmacodynamic measures in both animals and humans. Includes comprehensive coverage of biomarker tools and the role of personalized medicine in CNS drug development Discusses strategies for drug development for a full range of CNS indications, with particular attention to neuropsychiatric and neurocognitive disorders Includes chapters written by international experts from industry and academia