Therapeutic Strategies to Overcome ALK Resistance in Cancer
  • Release Date : 18 January 2021
  • Publisher : Academic Press
  • Categories : Science
  • Pages : 216 pages
  • ISBN 13 : 9780128217795
  • ISBN 10 : 0128217790
Score: 4
From 245 Ratings
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Synopsis : Therapeutic Strategies to Overcome ALK Resistance in Cancer written by Luc Friboulet, published by Academic Press which was released on 18 January 2021. Download Therapeutic Strategies to Overcome ALK Resistance in Cancer Books now! Available in PDF, EPUB, Mobi Format. Therapeutic Strategies to Overcome ALK Resistance in Cancer, Volume 13, presents current strategies to improve and prolong clinical benefit in ALK driven cancers. Most patients with ALK-driven cancer are sensitive to tyrosine kinase inhibitor (TKI) therapy, but resistance invariably develops. This book discusses topics such as structure and function of ALK, ALK rearranged lung cancer, resistance mechanisms to ALK TKI tumors, and novel therapeutic strategies to enhance crizotinib anti-tumor efficacy in ALCL. Additionally, it encompasses information on drug combinations to enhance ALK TKI anti-tumor efficacy in neuroblastoma and future perspectives in the field. This book is a valuable resource for cancer researchers, clinicians and several members of biomedical field who need to understand more about how to fight ALK resistance in cancer treatment. Explains the biology of ALK RTK, focusing on its tissue expression, structure and functionality Presents an overview of current treatments and the benefits of ALK TKI in lung and other cancer types, such as ALCL, neuroblastoma and inflammatory myofibroblastic tumor Encompasses information on systemic treatments other than TKI, including chemotherapy, immunotherapy and antiangiogenic agents in ALK-driven NSCLC

Lung Cancer

Lung Cancer

Author : Alba Fabiola Costa Torres
Publisher : BoD – Books on Demand
Category : Medical
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